tag:blogger.com,1999:blog-30206473.post5687861426930554084..comments2023-10-23T11:24:13.532-04:00Comments on Diabetes Update: Berberine Works But May Very Well Be HarmfulJennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.comBlogger27125tag:blogger.com,1999:blog-30206473.post-89712335781750797142015-05-23T21:46:04.368-04:002015-05-23T21:46:04.368-04:00It's very simple. JESUS naturally gave us ev...It's very simple. JESUS naturally gave us everything we need from the earth and not a pharmaceutical lab. Everything isn't for everybody and no two people are metabolically the same. I can only speak from my own experience and all I can say is my husband's type 2 diabetes has been reversed and berberine was a major part in his reversal in only 3 short months. His A1C levels afterAnonymoushttps://www.blogger.com/profile/16784666428617197250noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-58083373076353916212015-03-04T18:46:05.958-05:002015-03-04T18:46:05.958-05:00Pharmaceuticals are NOT studied long-term either. ...Pharmaceuticals are NOT studied long-term either. One-year trials do not account for 5-10+ years of use, just as you say about herbs. MooseSlaphttps://www.blogger.com/profile/03483498715853355813noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-55714662643144862012015-02-16T12:50:15.638-05:002015-02-16T12:50:15.638-05:00Thankyou Steve !Thankyou Steve !Persephonehttps://www.blogger.com/profile/03479448534245049624noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-84057474946997891062015-01-21T19:57:55.307-05:002015-01-21T19:57:55.307-05:00In vitro studies demonstrating "cell damage&q...In vitro studies demonstrating "cell damage" by a substance mean next-to-nothing to me. I can demonstrate "cell damage" with in vitro tests using coffee, tea, vinegar, orange juice, ketchup, distilled water, and numerous other substances regularly used by people without any harm. That's because in vitro tests are just test tube studies on an artificially grown cell line.Steve Barwickhttps://www.blogger.com/profile/07609959967400251679noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-81141973531175474592014-06-01T23:10:45.227-04:002014-06-01T23:10:45.227-04:00Whether you take berberine or a pharma drug you wi...Whether you take berberine or a pharma drug you will enventually die at some point in time from something. All the studies in the world are just that. The problem with pharma and herbalists is they are both after whats in your wallet. Ive taken berberine with good results however it isnt a cure all. It doesnt always work well if i continue to eat alot of sugar. Arnica 6x with protein and alpha beta circuloidhttps://www.blogger.com/profile/13662071056901598629noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-50442043701166180542014-04-04T14:00:36.964-04:002014-04-04T14:00:36.964-04:00>To get a feel for the quality of the research ...>To get a feel for the quality of the research supporting >the claims about berberine, scroll down to the >Reference section of this page: http://examine.com>/supplements/Berberine/ . <br /><br />You make several very relevant points but there are two weaknesses that worry me. One is, that you don't do an apples to apples comparison of the dangers of metformin and berberine Michlhttps://www.blogger.com/profile/04383806284487473852noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-45442608001184098592013-12-02T22:09:05.677-05:002013-12-02T22:09:05.677-05:00I'll take my chances with berberine.I'll take my chances with berberine. <br />conchchowderhttps://www.blogger.com/profile/16323785232048742925noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-84765860034462484492013-12-02T22:08:41.561-05:002013-12-02T22:08:41.561-05:00I'll take my chances with berberine.I'll take my chances with berberine. <br />conchchowderhttps://www.blogger.com/profile/16323785232048742925noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-81378075335386219212013-10-11T14:58:37.692-04:002013-10-11T14:58:37.692-04:00Jenny,
Thanks for the info. I had to give up Met...Jenny,<br /><br />Thanks for the info. I had to give up Metformin HCl due to Pain on my back and shoulder when I had to take 4x500 mg a day. <br /><br />Berberine probably will cause more long term ill effects, as the literature start to illustrate.<br /><br />This is a good site. Good job.Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-60172803590560562552013-10-11T13:56:53.181-04:002013-10-11T13:56:53.181-04:00Jonathan,
The body does not become resistant to ...Jonathan, <br /><br />The body does not become resistant to metformin. The only reason metformin appears to become ineffective is that people who take it are told by their doctors to keep their blood sugars at levels high enough to slowly kill their remaining beta cells. If you keep your blood sugar under 140 mg/dl (7.7 mmol/L) at all times, metformin will continue to be effective for decades. <Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-69848935431405415422013-10-11T13:09:08.529-04:002013-10-11T13:09:08.529-04:00Atrogin-1 affects muscle protein synthesis and deg...Atrogin-1 affects muscle protein synthesis and degradation when energy metabolism is impaired by the antidiabetes drug berberine.<br />Wang H, Liu D, Cao P, Lecker S, Hu Z.<br />http://www.ncbi.nlm.nih.gov/pubmed/20522589#Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-29306897863086934172013-10-11T13:06:31.332-04:002013-10-11T13:06:31.332-04:00
Hi,
You can hardly find any negative rep...<br /> Hi,<br /><br /> You can hardly find any negative report on Berberine. I manged to find one in WebMed.<br /><br /> This case almost clearly stated that people with heart problems can be induced by Berberine to have arrhythmias attack. It is a interesting case indeed.. Berberine has an unique effect on heart functions.<br /><br /> [ Reviewer: 25-34 Female on Treatment for less Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-11161767006685825622013-10-11T13:02:00.053-04:002013-10-11T13:02:00.053-04:00
Another interesting non-peer-reviewed paper
...<br /> Another interesting non-peer-reviewed paper<br /> MicroRNA-21-3p, a Berberine-Induced miRNA, Directly Down-Regulates Human Methionine Adenosyltransferases 2A and 2B and Inhibits Hepatoma Cell Growth http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075628 from Taipei, Taiwan. A splendid work. But the results can point to either way Because the main claim of the Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-49910784999477796772013-10-11T13:00:38.749-04:002013-10-11T13:00:38.749-04:00my fellow diabetes:
By now, my fellow diabetes! Yo...my fellow diabetes:<br />By now, my fellow diabetes! You must have heard this ancient Chinese over the counter herbal pills. If you browse over Google, amazon.com you will see thousands of endorsement from those Las Vegas witness stands. Those Chinese professors ‘xixo’ have pumped up publication in pre-peer-review Journals. They all claim Berberine is better than metformin. Berberine, this class Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-71524773370154807032013-10-10T20:17:28.317-04:002013-10-10T20:17:28.317-04:00Jonathan,
Thanks for posting these illuminating t...Jonathan,<br /><br />Thanks for posting these illuminating toxicology reports!Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-40574352638763832412013-10-10T19:32:43.020-04:002013-10-10T19:32:43.020-04:00Hi, Janet
I would like to share a little newest in...Hi, Janet<br />I would like to share a little newest information of Berberine. <br /><br />/Berberine/DNA damaging/ protein synthesis initiation inhibition/ tumorgenicity/ Carcinogen<br />There are many reports on the subject of Berberine: <br />peer reviewed and pre-reviewed journals, online and not online.<br />The government FDA/NCTR (National Center for Toxicology Research) has had both the Anonymoushttps://www.blogger.com/profile/13234889254740819478noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-60453127626483768902013-09-13T22:48:27.085-04:002013-09-13T22:48:27.085-04:00I considered taking berberine when I heard all the...I considered taking berberine when I heard all the glowing reports. But finding out it is a DPP-4 inhibitor made me decide against it. Another reason I do not want to take it is that it is also an antimicrobial and I wonder what it does to gut flora. Annehttps://www.blogger.com/profile/16655747133135789559noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-62691355324772028052013-08-23T13:42:27.939-04:002013-08-23T13:42:27.939-04:00Jenny,
Thank you for the additional research and ...Jenny,<br /><br />Thank you for the additional research and info on metformin!Dariahttps://www.blogger.com/profile/07943258318454929706noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-69801525531982508702013-08-21T14:15:20.757-04:002013-08-21T14:15:20.757-04:00RLL,
That is wonderful news and should be very en...RLL,<br /><br />That is wonderful news and should be very encouraging to others who are dealing with a retinopathy diagnosis! Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-19251470437435226662013-08-21T13:17:27.076-04:002013-08-21T13:17:27.076-04:00Jenny - this is off topic, but maybe of interest. ...Jenny - this is off topic, but maybe of interest. My Ophth. discovered my retinopathy about eight years ago, and encouraged getting BGs to true normal. He did the required surgery and noted that there was some peripheral ongoing retinopathy which was not particularly threatening. I have kept my A1Cs at 4.8-5.1. He was amazed at a regular checkup last month to see that even that retinopathy is RLLhttps://www.blogger.com/profile/13850927095383579725noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-3499163648053109922013-08-17T09:27:59.546-04:002013-08-17T09:27:59.546-04:00Looking into the issue of Metformin and AD further...Looking into the issue of Metformin and AD further, I have found a mix of findings. Rodent studies suggest metformin does cross the blood brain barrier and that it can cause more deposit of amyloid. OTOH, taking metformin with insulin appears to reverse this process. Insulin fights the deposit of amyloid and when taken with metformin does a better job.<br /><br />Meanwhile, on the epidemiologicalJennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-20371487189657856672013-08-15T14:51:24.118-04:002013-08-15T14:51:24.118-04:00Daria,
I would not leap to conclusions about the ...Daria,<br /><br />I would not leap to conclusions about the effect of metformin on Alzheimers based mainly on mouse research in one strain of genetically modified mice. <br /><br />Other epidemiological studies have come up with results that are all over the place. Some show metformin <i>reducing the incidence of Alzheimers</i>. Some show a very small rise. None appear to look at the actual bloodJennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-54770682118809392502013-08-15T13:49:44.853-04:002013-08-15T13:49:44.853-04:00Jenny, thank you for your answer!
Agree on danger...Jenny, thank you for your answer! <br />Agree on danger of any abnormally elevated blood sugar, but have to disagree about metformin. It looks that metformin’s connection to Alzheimer’s is about AMPK overactivation.<br />http://www.scripps.edu/news/press/2013/20130410polleux.html<br />Also, it looks like “long-term use of sulfonylureas, thiazolidinediones, or insulin was not associated with an Dariahttps://www.blogger.com/profile/07943258318454929706noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-85030602283171061932013-08-15T10:54:43.228-04:002013-08-15T10:54:43.228-04:00Sol,
I did not in any way ignore the actions that...Sol,<br /><br />I did not in any way ignore the actions that cause blood sugar to lower. They were activating AMP-Kinase, inhibiting DDP-4 and raising GLP-1 levels (which is accomplished by inhibiting DPP-4, the protease that cuts up that enzyme.)<br /><br />My web site documents in great detail why inhibiting DPP-4 and raising GLP-1 levels may be very dangerous. <br /><br />Having relatives withJennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-32651334621187981342013-08-15T10:38:26.307-04:002013-08-15T10:38:26.307-04:00Hiya Jenny,
I'm from Examine.com. I'd poi...Hiya Jenny,<br /><br />I'm from Examine.com. I'd point out that it's a false connection to say "x can damage your body while lowering blood sugar" while completing ignoring the actual actions that cause the blood sugar to lower.<br /><br />As for me not knowing about diabetes. I've had grandparents on both sides of the family die, one side from Type 1, and the other sideSol Orwellhttps://www.blogger.com/profile/07568040523053388580noreply@blogger.com