tag:blogger.com,1999:blog-30206473.post267359902730289266..comments2023-10-23T11:24:13.532-04:00Comments on Diabetes Update: News You Missed: Actos Strongly Linked to RetinopathyJennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.comBlogger11125tag:blogger.com,1999:blog-30206473.post-13590442701695238202009-08-21T14:07:41.341-04:002009-08-21T14:07:41.341-04:00Don,
Your story is so tragic. My own experience ...Don, <br /><br />Your story is so tragic. My own experience with serious side effects is that doctors are so scared of law suits they will become very dishonest when a serious side effect occurs. <br /><br />You might consider contacting a good personal injury attorney because you need the services and adaptive devices that could let you continue to be productive. Find someone who specializes in Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-84175826723244287292009-08-21T13:51:56.345-04:002009-08-21T13:51:56.345-04:00This may come up as anonymous, but I am Don. I w...This may come up as anonymous, but I am Don. I wanh all to know that i am not hiding behind anything.<br />I took Actos Plus Met for almost 2 years. After two months I was diagnosed with a Central Retinal Vein Oclusion in the right eye. Two months later, same thing in the left eye. I informed my doctor who promptly increased my Actos dose. My HA1c was 5.7. Long story short. After 3 years Unknownhttps://www.blogger.com/profile/01044610204243172454noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-37659222429869723232009-06-26T22:57:56.098-04:002009-06-26T22:57:56.098-04:00After taking actos for only two days I started exp...After taking actos for only two days I started experiencing all the symptoms of someone with congestive heart failure - extreme shortness of breath, fatigue, a dry cough and wheezing. I could not walk from my kitchen to the bathroom without being out of breath. Dressing and bathing were ordeals. Has anyone else had such a rapid negative response to this drug? I just wanted to tell someone -I wantMookiehttps://www.blogger.com/profile/08748927053305998306noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-87706075066908111512009-05-05T08:41:00.000-04:002009-05-05T08:41:00.000-04:00"Diabetes" is really many different disorders with..."Diabetes" is really many different disorders with a common symptom, high blood sugars.<br /><br />Indeed, and sometimes the BG doesn't actually have to be that high to induce a lot of diabetic symptoms, particularly the dyslipidemia.<br /><br />Once again there appears to be a small population for whom Byetta simply doen't work. Probably all drugs work for some and not for others and in the Big Trinkwassernoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-20972286658617881652009-05-04T21:16:00.000-04:002009-05-04T21:16:00.000-04:00interestingly enough, insulin and meglitinde also ...interestingly enough, insulin and meglitinde also showed an increased risk of macular edema - while metformin and acarbose showed they didn't increase the risk. This is from a study in the journal of opthamology in feb 2009. the increased risk of fractures in post menapausal women seems to be the real risk in the tzd class when the doctors use these drugs appropriatelyAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-85378139288667502452009-04-30T06:46:00.000-04:002009-04-30T06:46:00.000-04:00There is a population for whom carb restriction do...There is a population for whom carb restriction doesn't work. They are usually people who require several hundred units a day of insulin (up to 500!) to get near normal numbers.<br /><br />Two people I know who fall into that category have done extremely well on Byetta, but on nothing else. <br /><br />"Diabetes" is really many different disorders with a common symptom, high blood sugars.<br /><Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-65436691329804078122009-04-30T03:28:00.000-04:002009-04-30T03:28:00.000-04:00TZDs have turned into something of a disappointmen...TZDs have turned into something of a disappointment. They attacked insulin resistance through a different process than metformin, but oh dear don't they seem to adversely affect other systems?<br /><br />So what's left to attack IR? Gosh, reducing carbs! The Horror! Side effects include hugely improved lipids and reduced BP and general reduction in all cardiovascular risk factors.<br /><br />I Trinkwassernoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-23277158002145649862009-04-29T17:59:00.000-04:002009-04-29T17:59:00.000-04:00The cell culture study is well known, but it is a ...The cell culture study is well known, but it is a huge leap from cell cultures to people. Avandia looked good in cell cultures too, but over time, people who took it saw their beta function decrease, not increase and there is zero evidence of beta regrowth with TZDs or Byetta.<br /><br />The point of regrowing beta cells is to to increase insulin secreting capacity. If that capacity drops rather Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-45156869370582481092009-04-29T17:24:00.000-04:002009-04-29T17:24:00.000-04:00http://www.ncbi.nlm.nih.gov/pubmed/12960095?dopt=A...http://www.ncbi.nlm.nih.gov/pubmed/12960095?dopt=AbstractAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-2763057862635833672009-04-29T16:27:00.000-04:002009-04-29T16:27:00.000-04:00The study found an association, but this is not th...The study found an association, but this is not the first study I've read that flagged the issue. It's just the largest. <br /><br />We already know that these drugs cause edema in other contexts--and that's not an association, it's a known side effect.<br /><br />The biggest issue with tight control in hospital situations is the way insulin is dosed--without reference to incoming carbs, but Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-5280788652270523252009-04-29T15:58:00.000-04:002009-04-29T15:58:00.000-04:00Jenny,
First off, I want to thank you, as always, ...Jenny,<br />First off, I want to thank you, as always, for the tremendous service you provide in bringing to light all the clinical data and empowering diabetics to improve their care. I read your blog not to evoke hostility but to inform myself, and have never been interested in personal attacks. I do take the aforementioned drug along with metformin and byetta and am very happy and well Anonymousnoreply@blogger.com