tag:blogger.com,1999:blog-30206473.post1692807858429729144..comments2023-10-23T11:24:13.532-04:00Comments on Diabetes Update: What I'd Like to See Change at the FDAJennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.comBlogger8125tag:blogger.com,1999:blog-30206473.post-25736026084268521682009-03-02T02:43:00.000-05:002009-03-02T02:43:00.000-05:00First, in the study you are referring to it was ac...First, in the study you are referring to it was actually .9%. <BR/><BR/>Second, what makes you think Byetta is so safe? They haven't completed a macrovascular outcomes trial, and they have no fda approved safety data in their PI. Is it really a good idea to take a drug just because nothing has been reported yet? Ignorance is not always bliss. <BR/><BR/>Thirdly, there is such a thing as mild Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-2731271619932997172009-02-28T07:17:00.000-05:002009-02-28T07:17:00.000-05:00Anonymous,The lowering of A1c after 26 weeks repor...Anonymous,<BR/><BR/>The lowering of A1c after 26 weeks reported in the official Actos prescribing information is .3 to .8% in a population whose average A1c was 10%. <BR/><BR/>The very small number of deaths from pancreatitis found with Byetta--6, and it is not clear if there is causation, palls next to the deaths from unnecessary heart failure from Actos.<BR/><BR/>There is no such thing as "Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-1029390938254434802009-02-28T00:08:00.000-05:002009-02-28T00:08:00.000-05:00Actos can lower A1C up to 2.6% points. With Metfo...Actos can lower A1C up to 2.6% points. With Metformin, and Byetta your looking around 1.5%. Sulfonylureas can get you close to a 2% drop, but then you have to deal with bouts of hypoglycemia which can be very dangerous, and sulfs also contribute to an accelerated drop in beta cell function. Byetta increases your risk of pancreatitis, and the last few instances of pancreatitis have been fatal Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-2441101008152586002009-02-27T07:52:00.000-05:002009-02-27T07:52:00.000-05:00Counteracting the studies you cite (which I have n...Counteracting the studies you cite (which I have not been able to read in full text to see exactly how they were conducted and to what extent they were controlled by Takeda) are those that show that Actos CAUSES heart failure in younger people who were fine before they started it, that it increases the likelihood of retinal edema (which leads to blindness) and that it causes bone bone fractures Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-19347650801765817292009-02-27T02:17:00.000-05:002009-02-27T02:17:00.000-05:00Jenny, I can't help but notice that you are not a ...Jenny, I can't help but notice that you are not a fan of TZD's at all. I agree that Avandia should have been taken off the market in 1999. However, Actos, I believe is a far far superior drug. You said,"When they die unnecessarily taking a drug that makes only a tiny difference in their blood sugars as is the case with TZDs," What drug has a better A1C drop then Actos, and for as long? You Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-37249272392685002262008-12-30T11:48:00.000-05:002008-12-30T11:48:00.000-05:00New Year's Resolution: Watch and think about "Swee...New Year's Resolution: Watch and think about "Sweet Misery." This was shown recently on the Documentary Channel. It is so perverse, and because aspartame is such a godsend for diabetics longing for a 'taste of sweet' without the penalties, it seems they are doubly victimized.<BR/><BR/>The 'market' may take care of false advertising and pseudo-science . . . but how many are harmed in the meantime.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-30206473.post-32970752218855172882008-12-28T11:09:00.000-05:002008-12-28T11:09:00.000-05:00SnowDog,"If people lie or make false claims this i...SnowDog,<BR/><BR/>"If people lie or make false claims this information will get into the market too".<BR/><BR/>It took 10 years for the news that Avandia causes irreversible osteoporosis to hit the market--this is going to kill a lot of older women. <BR/><BR/>It will take at least that long for doctors to realize that Januvia energizes cancer. <BR/><BR/>Thousands of people may die unnecessary Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-73016664840060932962008-12-28T09:50:00.000-05:002008-12-28T09:50:00.000-05:00Ah Jenny, you want to use force in so many differe...Ah Jenny, you want to use force in so many different ways. Don't you know that force is backed by threats of violence at the point of a gun?<BR/><BR/>Let people say what they want, test the way they want, and claim whatever they want. Don't hinder new drugs from coming to market. If people lie or make false claims, this information will get into the market too; those responsible will lose their SnowDoghttps://www.blogger.com/profile/10384813683687359354noreply@blogger.com