tag:blogger.com,1999:blog-30206473.post1095993491349717953..comments2023-10-23T11:24:13.532-04:00Comments on Diabetes Update: Before You Choose Weight Loss Surgery Read ThisJennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.comBlogger9125tag:blogger.com,1999:blog-30206473.post-89402117850208543592010-03-28T09:30:02.490-04:002010-03-28T09:30:02.490-04:00I had a good experience with Byetta until I had a ...I had a good experience with Byetta until I had a cortisone shot, which after I had to go on insulin. After starting Byetta (and getting used to its side effects,) I lost some weight, but my a1c dropped to around 5.4. I would recommend Byetta over any other of the drugs I take or have taken. I'm not happy on insulin, but I have no other options and have considered lap-band. Since I'm not Bozhttps://www.blogger.com/profile/08287680290391700918noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-56728083557232268942010-03-27T07:27:05.270-04:002010-03-27T07:27:05.270-04:00nyh,
The experimental surgery done on rodents mig...nyh,<br /><br />The experimental surgery done on rodents might be lower risk (no surgery done under anesthetic is 100% safe) and it has no significant track record yet in human to show the real risks. Very small studies such a have been done on it so far tend to paint too optimistic a picture and to be done on cherry picked patients.<br /><br />But most obese people with diabetes are not being Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-6959458670670050982010-03-27T02:29:16.227-04:002010-03-27T02:29:16.227-04:00C-reactive protein (CRP) is also a market for infl...C-reactive protein (CRP) is also a market for inflammatory bowel disease. In Crohn's disease it is too high to be measured on the hsCRP used to asses cardiac risk, but I have read that low-grade chronic inflammation of the intestinal lining which might result in undetected leaky gut syndrome often yields an hsCRP in the 5-10 range. I am postulating that the inflamed lining of the small Denny Barneshttps://www.blogger.com/profile/06952360626901939145noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-66500762846410195352010-03-26T21:43:08.394-04:002010-03-26T21:43:08.394-04:00You are incorrectly describing the surgery propose...You are incorrectly describing the surgery proposed for non obese type 2 diabetics. There is no amputation of the stomach or any other organ (of course the "A" word is inflammatory to any diabetic). The surgery involves the bypassing of the duodenum and first part of the jejunum - nothing is amputated. The surgery is relatively simple and low risk and can be done laparoscopically.nyh gihttps://www.blogger.com/profile/05977269654323547367noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-72305529934362673062010-03-26T08:12:26.046-04:002010-03-26T08:12:26.046-04:00The CRP test reference in research is actually the...The CRP test reference in research is actually the "cardiac specific CRP" and wouldn't be a good index to inflammation in the gut.Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-56998780509463378512010-03-26T08:05:44.874-04:002010-03-26T08:05:44.874-04:00I have not seen any studies that measure inflammat...I have not seen any studies that measure inflammation after gastric bypass surgery. To test the inflammation theory, we would just need to see if C-reactive protein dropped after WLS surgery before there was significant weight-loss. Generally, CRP is highly correlated with insulin resistance.Denny Barneshttps://www.blogger.com/profile/06952360626901939145noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-84522894202150539962010-03-26T07:08:08.447-04:002010-03-26T07:08:08.447-04:00Denny,
If the problem were inflammation, surgery ...Denny,<br /><br />If the problem were inflammation, surgery wouldn't reverse it so quickly. Inflammation once established is very tough to reverse. <br /><br />I don't know the mechanism. One would hope researchers would look for it, but because of the focus on fixes rather than prevention, it's not likely they will.Jennyhttps://www.blogger.com/profile/17384082448952856117noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-51741598868480514992010-03-26T02:40:46.044-04:002010-03-26T02:40:46.044-04:00Why do you think the small intestine in Type 2 dia...Why do you think the small intestine in Type 2 diabetics has an impaired ability to release incretins to control insulin signaling? Interestingly, I wrote on lessons from gastric bypass surgery at http://anti-inflammatoryremarks.blogspot.com/ today. I postulate that gut inflammation is the underlying issue. Your thoughts?Denny Barneshttps://www.blogger.com/profile/06952360626901939145noreply@blogger.comtag:blogger.com,1999:blog-30206473.post-2835907762267609482010-03-26T01:06:13.487-04:002010-03-26T01:06:13.487-04:00I love byetta. I'm not diabetic but when I fir...I love byetta. I'm not diabetic but when I first heard of this drug several years ago I did research on it for a school project, and my thought was that this incretin mimetic is a very good therapy, in the same class as metformin (i.e. drugs that help resolve the underlying defects). Most traditional diabetic therapies seem to make things worse, or lower blood sugar at the cost of overall ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.com